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Ritonavir or lopinavir/ritonavir greatly raise plasma concentrations of oxycodone in balanced human volunteers on account of inhibition of CYP3A4 and CYP2D6.[fifty eight] Rifampicin considerably lowers plasma concentrations of oxycodone because of potent induction of CYP3A4.Drug interactions may change how your prescription drugs do the job or incr

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